In 2010, Phage Technologies kicked off the technology development used in Fagolac®. After 3 years of development, the first version of the product was introduced in the chilean market under the brand Milkeeper®. 3 years later, Bayer Animal Health® took the technology to make it available for its costumers to make it avaiable for their costumers from from Latin America.
Fagolac® 100g - 2018
Fagolac® is a food additive in powder for calves, able to control the prescence of E.coli (EHEC and ETEC) and Salmonella spp. (Serotypes Typhimurium, Dublin, Panama and Mbandaka).
Bacteriophage used on Fagolac®
For this, we use a specific bacteriophage cocktail against a set of bacterial receptors that allows:
1. Eliminate pathogenic or antibiotic resistant bacterias preventing infections.
2. Protect the Ruminal and comensal flora bacteria and in this way increasing animal gut health.
3. Preventive effect, avoiding the subclinical effect of the pathogenic bacterial strains.
4. Increase animal weight gain.
The bacteriophage are microencapsuled in a food grade excipient hydrolyzed with 200 micron particles size.
The excipient formula DOES NOT change any organoleptic features of the milk. and allows a fast and easy homogenization with liquids. Protecting the bacteriophages during 24 months before use.
Fagolac's ® bacteriophages, cross for the whole diggestive tract until reach the animal intestine, where they make a strong binding with the intestinal mucus. Generating a bacteriophage minefield against the target bacterias, avoiding the pathogen colonization.
Bacteriophage-bacteria colonization illustration. 1. Mucus secretion; 2. Bacteriophage administration 3. bacteriophage-mucus binding 4. Pathogenic E.coli arrival 5. Bacterial infection and lysis. 6. New bacteriophage release; 7. Bacteriophage discard by peristaltic movements.
The use of the bacteriophages in milk or dairy replacer, for the 60 first rearing days, allows avoid the bacterial colonization in the animal intestine.
The use of FAGOLAC® during the first 60 rearing days reduces at 67% the losses related to E.coli y Salmonella (USD 250/calve).
Related losses like:
Weight gain losses.
Genetics and insemination expenses.
Modo de uso Fagolac® - Milkeeper®